NEWGARDE ORAL SOLUTION FOR POULTRY 1000ml (ENROFLOXACIN, KOLISTIN SULFATE, TILMICOSIN)
Description
Liquid from light yellow to dark yellow, slight sediment is allowed.
Composition
1 ml of the drug contains active ingredients:
enrofloxacin - 80 mg;
colistin sulfate - 600,000 IU;
tilmicosin - 75 mg.
Pharmacological properties
Newgard is a combination drug containing three antibiotics.
Enrofloxacin is an antibiotic of the fluoroquinolone group. The mechanism of its action is associated with the inhibition of the a subunit of DNA gyrase (topoisomerase ii) of gram-negative bacteria, which blocks the process of supercoiling of the DNA molecule. In gram-positive bacteria, this process affects topoisomerase iv rather than topoisomerase ii. under these conditions, transcription and recombination processes in the bacterial DNA are blocked.
Enrofloxacin has a bactericidal effect against gram-positive (Staphylococcus spp., Streptococcus spp., Clostridium spp., Listeria monocytogenes, Corynebacterium spp. And others) and gram-negative microorganisms (E. coli, Salmonella Pasureus spp., Klebsiella spp., Proteus ., Bordetella spp., Etc.), and also acts on mycoplasmas (Mycoplasma gallisepticum, Mycoplasma synoviae, Mycoplasma hyosynoviae, Mycoplasma hyopneumoniae, Mycoplasma meleagridis, Mycoplasma iowae).
Colistin is an antibiotic of the polymyxin group, synthesized by the aerobic spore-forming bacillus bacillus polymyxa. it acts bactericidal on gram-positive bacteria (such as E. coli, Salmonella spp., Pseudomonas spp.), binding to phospholipids of the cytoplasmic membrane, increasing its permeability to both internal and external cellular components, which leads to the destruction of cellular barriers.
Tilmicosin is a semi-synthetic antibiotic of the macrolide group with a broad spectrum of action against gram-positive and gram-negative microorganisms, especially against Pasteurella spp., Haemophilus spp., Actinomyces spp., Corynebacterium and Mycoplasma spp. the mechanism of action of tilmicosin is to block the synthesis of proteins in a bacterial cell as a result of the formation of a complex with the 50s-subunits of ribosomes.
Application
Treatment of poultry (chickens, broiler chickens, turkeys) suffering from colibacillosis, pasteurellosis, salmonellosis, mycoplasmosis, chronic respiratory infections, staphylococcosis and campylobacteriosis caused by microorganisms sensitive to enrofloxacin and colistinucosis.
Dosage
Orally with drinking water at a dose of 1.0 ml of the drug per 1 liter of drinking water daily for 3-5 days.
Depending on the severity of the disease, the dose of the drug can be increased to 1.5 ml of the drug per 1 liter of drinking water daily.
Treatment can be repeated later in case of stressful situations and new cases of the disease.
Shake the ampoule or bottle (canister) with the drug before use.
During the treatment period, animals should receive only water containing the drug. Every day, a fresh solution of the drug is prepared in a volume calculated for consumption throughout the day.
Contraindications
Hypersensitivity to enrofloxacin, tilmicosin and colistin.
Do not use in poultry with severe renal and hepatic impairment.
Do not use concomitantly with tetracyclines, erythromycin, cyclosporins, chloramphenicol, as well as non-steroidal anti-inflammatory drugs.
Do not use in laying hens whose eggs are intended for human consumption.
Warning
In the recommended doses, side effects are usually not observed.
Slaughter of poultry for meat is allowed 12 days after the last use of the drug. The meat obtained before the specified time is disposed of or fed to unproductive animals, depending on the conclusion of the veterinary doctor.
Storage
Dry, dark place out of the reach of children at temperatures from 5 ° C to 25 ° C. Do not freeze.
Shelf life is 2 years.
MANUFACTURER: O.L.KAR UKRAINE
Free shipping to USA and UK
Description
Liquid from light yellow to dark yellow, slight sediment is allowed.
Composition
1 ml of the drug contains active ingredients:
enrofloxacin - 80 mg;
colistin sulfate - 600,000 IU;
tilmicosin - 75 mg.
Pharmacological properties
Newgard is a combination drug containing three antibiotics.
Enrofloxacin is an antibiotic of the fluoroquinolone group. The mechanism of its action is associated with the inhibition of the a subunit of DNA gyrase (topoisomerase ii) of gram-negative bacteria, which blocks the process of supercoiling of the DNA molecule. In gram-positive bacteria, this process affects topoisomerase iv rather than topoisomerase ii. under these conditions, transcription and recombination processes in the bacterial DNA are blocked.
Enrofloxacin has a bactericidal effect against gram-positive (Staphylococcus spp., Streptococcus spp., Clostridium spp., Listeria monocytogenes, Corynebacterium spp. And others) and gram-negative microorganisms (E. coli, Salmonella Pasureus spp., Klebsiella spp., Proteus ., Bordetella spp., Etc.), and also acts on mycoplasmas (Mycoplasma gallisepticum, Mycoplasma synoviae, Mycoplasma hyosynoviae, Mycoplasma hyopneumoniae, Mycoplasma meleagridis, Mycoplasma iowae).
Colistin is an antibiotic of the polymyxin group, synthesized by the aerobic spore-forming bacillus bacillus polymyxa. it acts bactericidal on gram-positive bacteria (such as E. coli, Salmonella spp., Pseudomonas spp.), binding to phospholipids of the cytoplasmic membrane, increasing its permeability to both internal and external cellular components, which leads to the destruction of cellular barriers.
Tilmicosin is a semi-synthetic antibiotic of the macrolide group with a broad spectrum of action against gram-positive and gram-negative microorganisms, especially against Pasteurella spp., Haemophilus spp., Actinomyces spp., Corynebacterium and Mycoplasma spp. the mechanism of action of tilmicosin is to block the synthesis of proteins in a bacterial cell as a result of the formation of a complex with the 50s-subunits of ribosomes.
Application
Treatment of poultry (chickens, broiler chickens, turkeys) suffering from colibacillosis, pasteurellosis, salmonellosis, mycoplasmosis, chronic respiratory infections, staphylococcosis and campylobacteriosis caused by microorganisms sensitive to enrofloxacin and colistinucosis.
Dosage
Orally with drinking water at a dose of 1.0 ml of the drug per 1 liter of drinking water daily for 3-5 days.
Depending on the severity of the disease, the dose of the drug can be increased to 1.5 ml of the drug per 1 liter of drinking water daily.
Treatment can be repeated later in case of stressful situations and new cases of the disease.
Shake the ampoule or bottle (canister) with the drug before use.
During the treatment period, animals should receive only water containing the drug. Every day, a fresh solution of the drug is prepared in a volume calculated for consumption throughout the day.
Contraindications
Hypersensitivity to enrofloxacin, tilmicosin and colistin.
Do not use in poultry with severe renal and hepatic impairment.
Do not use concomitantly with tetracyclines, erythromycin, cyclosporins, chloramphenicol, as well as non-steroidal anti-inflammatory drugs.
Do not use in laying hens whose eggs are intended for human consumption.
Warning
In the recommended doses, side effects are usually not observed.
Slaughter of poultry for meat is allowed 12 days after the last use of the drug. The meat obtained before the specified time is disposed of or fed to unproductive animals, depending on the conclusion of the veterinary doctor.
Storage
Dry, dark place out of the reach of children at temperatures from 5 ° C to 25 ° C. Do not freeze.
Shelf life is 2 years.
MANUFACTURER: O.L.KAR UKRAINE
Free shipping to USA and UK