Ronidazole 30 mg. - tablets for cats, dogs, birds 50 tab.
Description
Tablets of a rounded shape from white to yellow in color, with a specific smell of the constituent components.
Storage
One tablet (weighing 120 mg) contains the active substance:
ronidazole - 30 mg.
Excipients: polyvinylpyrrolidone, potato starch, calcium stearate, talc, albumin, powdered milk, flavoring, lactose.
Pharmacological properties
ATCvet QP51, antiprotozoal veterinary drugs.
Ronidazole (a group of nitroimidazole compounds) acts on protozoa, trichomonas and anaerobic bacteria. The connection of the reaction products of ronidazole with the DNA of the simplest cells or bacteria leads to its death. The formation of strong compounds significantly increases the acidic intracellular pH level, which, among other things, confirms the selective action of 5-nitromidazole derivatives against anaerobic bacteria and some protozoa. In addition, as a result of the reaction of ronidazole, products are created, which are intracellular donors of aerobic free radicals, which additionally damage intracellular molecules other than DNA. This increases cellular destruction and leads to the fastest death of protozoa or bacteria.
After oral administration, ronidazole is almost completely quickly absorbed from the digestive tract and reaches the maximum concentration in the blood plasma after 12-14 hours. Its bioavailability is more than 90%. The plasma half-life of ronidazole after oral administration in most animals is approximately 11 hours, blocking its reproduction by inhibiting DNA synthesis. Ronidazole, when administered to animals as a single oral dose, has shown that 30-36% of the dose is excreted in the urine and 16-40% in the feces within 24 hours. Further excretion is slow and incomplete.
The drug in the recommended doses has no sensitizing, embryotoxic and teratogenic effects.
Application
Prevention and treatment of pigeons and decorative birds for trichomoniasis (Trichomonas gallinae), hexamithiasis (Hexamita columbae), Cochlosoma spp. and other protozoan diseases, dogs and cats with diseases of the gastrointestinal tract and other organs and tissues caused by the simplest Trichomonas spp. Giardia spp.
Dosage
Dogs: in the treatment of animals affected by Giardia spp. tablets are used orally, once a day at a dose of 30-50 mg per 1 kg of the animal's body weight, a course of 7 days.
Cats: in the treatment of animals affected by giardiasis, tablets are used orally, once a day, in a dose of 30 mg per 1 kg of the animal's body weight for 7 days.
In the treatment of infections caused by Trichomonas foetus, the drug is used orally once a day at a dose of 30 mg per 1 kg of the animal's body weight for a course of 14 days.
Pigeons: For the treatment and prevention of trichomonosis (Trichomonas gallinae), hexamithiasis (Hexamita columbae) and other protozoan diseases in pigeons and decorative birds.
The recommended prophylactic dose is 1 tablet per pigeon. Course of treatment: 1-3 days.
The recommended therapeutic dose is 1 tablet per pigeon. Course of treatment: 3-5 days.
Contraindication
Increased sensitivity to the components of the drug.
Do not use in cats, dogs and poultry with signs of viral infection, disorders of the functions of the nervous system, kidneys and liver.
Do not use in pregnant or lactating animals.
Reservation
Use the drug according to the recommendations for use. The recommended doses should be followed. Treatment of animals and birds should be combined with disinfection of premises, enclosures, cages where sick animals and birds are kept, in order to avoid the possibility of re-infection. Pets should be bathed with shampoo in order to wash off the parasite spores that get on the fur.
Storage
Dry, dark, inaccessible to children and animals, place at a temperature of 5 to 25 °C.
Expiration date
3 years.
For use in veterinary medicine!
Description
Tablets of a rounded shape from white to yellow in color, with a specific smell of the constituent components.
Storage
One tablet (weighing 120 mg) contains the active substance:
ronidazole - 30 mg.
Excipients: polyvinylpyrrolidone, potato starch, calcium stearate, talc, albumin, powdered milk, flavoring, lactose.
Pharmacological properties
ATCvet QP51, antiprotozoal veterinary drugs.
Ronidazole (a group of nitroimidazole compounds) acts on protozoa, trichomonas and anaerobic bacteria. The connection of the reaction products of ronidazole with the DNA of the simplest cells or bacteria leads to its death. The formation of strong compounds significantly increases the acidic intracellular pH level, which, among other things, confirms the selective action of 5-nitromidazole derivatives against anaerobic bacteria and some protozoa. In addition, as a result of the reaction of ronidazole, products are created, which are intracellular donors of aerobic free radicals, which additionally damage intracellular molecules other than DNA. This increases cellular destruction and leads to the fastest death of protozoa or bacteria.
After oral administration, ronidazole is almost completely quickly absorbed from the digestive tract and reaches the maximum concentration in the blood plasma after 12-14 hours. Its bioavailability is more than 90%. The plasma half-life of ronidazole after oral administration in most animals is approximately 11 hours, blocking its reproduction by inhibiting DNA synthesis. Ronidazole, when administered to animals as a single oral dose, has shown that 30-36% of the dose is excreted in the urine and 16-40% in the feces within 24 hours. Further excretion is slow and incomplete.
The drug in the recommended doses has no sensitizing, embryotoxic and teratogenic effects.
Application
Prevention and treatment of pigeons and decorative birds for trichomoniasis (Trichomonas gallinae), hexamithiasis (Hexamita columbae), Cochlosoma spp. and other protozoan diseases, dogs and cats with diseases of the gastrointestinal tract and other organs and tissues caused by the simplest Trichomonas spp. Giardia spp.
Dosage
Dogs: in the treatment of animals affected by Giardia spp. tablets are used orally, once a day at a dose of 30-50 mg per 1 kg of the animal's body weight, a course of 7 days.
Cats: in the treatment of animals affected by giardiasis, tablets are used orally, once a day, in a dose of 30 mg per 1 kg of the animal's body weight for 7 days.
In the treatment of infections caused by Trichomonas foetus, the drug is used orally once a day at a dose of 30 mg per 1 kg of the animal's body weight for a course of 14 days.
Pigeons: For the treatment and prevention of trichomonosis (Trichomonas gallinae), hexamithiasis (Hexamita columbae) and other protozoan diseases in pigeons and decorative birds.
The recommended prophylactic dose is 1 tablet per pigeon. Course of treatment: 1-3 days.
The recommended therapeutic dose is 1 tablet per pigeon. Course of treatment: 3-5 days.
Contraindication
Increased sensitivity to the components of the drug.
Do not use in cats, dogs and poultry with signs of viral infection, disorders of the functions of the nervous system, kidneys and liver.
Do not use in pregnant or lactating animals.
Reservation
Use the drug according to the recommendations for use. The recommended doses should be followed. Treatment of animals and birds should be combined with disinfection of premises, enclosures, cages where sick animals and birds are kept, in order to avoid the possibility of re-infection. Pets should be bathed with shampoo in order to wash off the parasite spores that get on the fur.
Storage
Dry, dark, inaccessible to children and animals, place at a temperature of 5 to 25 °C.
Expiration date
3 years.
For use in veterinary medicine!