The powder is white.
Storage
1 g of the drug contains the active substance:
lincomycin hydrochloride – 22 mg;
Spectinomycin sulfate – 22 mg.
Excipients: lactose.
Pharmacological properties
Linkospekt 44 – combined preparation containing antibiotics – lincomycin and spektynomitsyn.
The drug has a broad spectrum antimicrobial activity against gram-positive and gram-negative bacteria.
Lincomycin – an antibiotic from the group linkozamidiv. It inhibits protein synthesis in microorganisms, connecting 50S ribosomal subunit of bacterial cells. The substance shows bacteriostatic or bactericidal, depending on the concentration. Lincomycin acts mainly on gram-positive bacteria, including Staphylococcus spp., Streptococcus spp., Bacillus anthracis, Corynebacterium spp., As well as on gram-negative bacteria: Actinobacillus spp., Bordetella spp., Some species Nocardia and Actinomyces spp., Particularly effective against Serpulina hyodysenteriae , Mycoplasma spp. etc.
Spektynomitsyn – tricyclic structure with an antibiotic aminoglycoside. The effectiveness of action associated with inhibition of protein synthesis in the microbial cell binding 30S ribosomal subunit microorganisms that prevent elongation of the polypeptide chain translocation to the stage. The substance acts mainly on gram-negative bacteria, including E. coli., Pasteurella multocida, Salmonella spp., Clostridium spp., Erysipelothrix rhusiopathiae, Haemophilus spp., Vibrio spp., As well as some Gram-positive microorganisms and Mycoplasma spp.
The combination of lincomycin and spektynomitsynu also effective in associates and chronic infections, against which antibiotics are ineffective other. The product is not toxic to animals and birds.
Application
Prevention and treatment of chickens (broilers, breeding chickens, replacement chicks) and porcine enzootic pneumonia, colibacillosis, salmonellosis, dysentery syndrome MMA (mastitis-metritis-agalactia), necrotic enteritis, mycoplasmosis and other diseases of the digestive tract and respiratory system caused by microorganisms sensitive to lincomycin and spektynomitsynu.
Batching
Oral with drinking water or food, individually or by group 1 per day in the following doses:
Pig:
for prophylaxis – 1 kg of the drug per 1 ton of feed for 5-7 days;
for treatment – 2 kg of the drug per 1 ton of feed for 5-7 days;
chickens (broilers, breeding chickens, Heifer):
for prophylaxis – 1 kg of the drug per 1 ton of feed for 5-7 days;
for treatment – 2 kg of the drug per 1 ton of food (1-2 kg drug in 1000 liters of drinking water), corresponding to 2.3 g of the drug per 1 kg of body weight for 5-7 days.
If necessary, treatment duration increased to 21 days.
Using the drug with food is recommended that you mix with 3-10% of the feed, and then stir the mixture with the remaining food.
Using the drug with the drinking water solution prepared from the calculation of the required number of drinking water for individual age categories poultry) for 1 day. Daily prepare a fresh solution of the drug.
Contraindication
Do not use in animals with hypersensitivity to lincomycin and spektynomitsynu.
Do not use chickens, laying hens, eggs which are intended for use in food to people.
The product is not used in conjunction with erythromycin.
Reservation
Slaughter pigs for meat is allowed after 3 days, poultry (chickens, broilers, breeding chickens, Heifer) – 2 days after the last use of the drug. Received by the deadline, or disposed of meat unproductive animals are fed, according to a doctor of veterinary medicine.
In some cases, after use of the drug in pigs may be redness of the skin and mucous membranes, which do not require discontinuation of therapy.
In the process of mixing the drug with food must use personal protection equipment (respirator, gloves).
Advance drug testing on a small group (9-10) heads of animals. In the absence of complications during 2-3 days the drug is used around livestock.
Product
Packages with a polymer film and / or metallic foil 100 g and 1 kg and / or bags of 10 and 25 kg.
Storage
Dry, dark, place inaccessible to children at temperature from 0 ° C to 25 ° C.
Shelf life – 2 years from date of manufacture. Shelf life: Mixed with food preparation – 24-36 hours; when dissolved in water – 24 hours.
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